| Verifiedrevid | 451225997 |
|---|---|
| Iupac name | Methyl (1R,2S,3S,5S)-3-(4-ethyl-3-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate |
| Width | 200px |
| Cas number | 198990-83-9 |
| Unii | ZSB3P8YAZ9 |
| Pubchem | 9801045 |
| C | 17 |
| H | 22 |
| I | 1 |
| N | 1 |
| O | 2 |
| Smiles | CCC1=C(C=C(C=C1)[C@H]2C[C@@H]3CC[C@H]([C@H]2C(=O)OC)N3)I |
RTI(-4229)-353 is a phenyltropane derived drug which acts as an SSRI.[1] Tamagnan et al. also made some phenyltropanes with high activity and selectivity for the SERT (pM affinity).[2]
See also
References
- ^ Navarro HA, Xu H, Zhong D, Blough BE, Ross WP, Kuhar MJ, Carroll FI (September 2001). "[(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter". Synapse. 41 (3): 241–7. doi:10.1002/syn.1081. PMID 11418937. S2CID 2323766
- ^ Tamagnan G, Alagille D, Fu X, Kula NS, Baldessarini RJ, Innis RB, Baldwin RM (January 2006). "Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes". Bioorganic & Medicinal Chemistry Letters. 16 (1): 217–20. doi:10.1016/j.bmcl.2005.09.016. PMID 16236497