| Iupac name | (8R,9S,13S,14S,16R,17R)-3-cyclopentyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol |
|---|---|
| Width | 250px |
| Tradename | Colpovis, Colpovister, Pentovis |
| Routes of administration | By mouth |
| Class | Estrogen; Estrogen ether |
| Cas number | 1169-79-5 |
| Unii | 422L8173W8 |
| Atc prefix | None |
| Pubchem | 14431 |
| Chemspiderid | 16735993 |
| Synonyms | Quinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE |
| C | 23 |
| H | 32 |
| O | 3 |
| Smiles | CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5CCCC5 |
| Stdinchikey | ODYKCPYPRCJXLY-PZORDLPLSA-N |
| Stdinchi | 1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1 |
Quinestradol (INN, BAN) (brand names Colpovis, Colpovister, Pentovis), also known as quinestradiol or quinestriol, as well as estriol 3-cyclopentyl ether (E3CPE), is a synthetic estrogen and estrogen ether which is no longer marketed.[1][2][3][4] It is the 3-cyclopentyl ether of estriol.[1] The medication has been studied in the treatment of stress incontinence in elderly women, with effectiveness observed.[3][4]
See also
References
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 899–. ISBN 978-1-4757-2085-3.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 905–. ISBN 978-3-88763-075-1.
- ^ Crosignani PG, Paoletti R, Sarrel PM, Wenger NK (6 December 2012). Women's Health in Menopause: Behaviour, Cancer, Cardiovascular Disease, Hormone Replacement Therapy. Springer Science & Business Media. pp. 245–. ISBN 978-94-011-1024-2.
- ^ Seifer DB (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 161–. ISBN 978-1-59259-246-3.