| Iupac name | (8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one |
|---|---|
| Cas number | 1961-77-9 |
| Unii | SDS4N642GG |
| Atc prefix | G03 |
| Atc suffix | DB06 |
| Pubchem | 5284533 |
| Chemspiderid | 4447590 |
| C | 21 |
| H | 27 |
| Cl | 1 |
| O | 3 |
| Smiles | O=C4\C=C3\C(\Cl)=C/[C@@H]1[C@H](CC[C@@]2([C@@](O)(C(=O)C)CC[C@@H]12)C)[C@@]3(C)CC4 |
| Stdinchi | 1S/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h10-11,14-16,25H,4-9H2,1-3H3/t14-,15+,16+,19-,20+,21+/m1/s1 |
| Stdinchikey | VUHJZBBCZGVNDZ-TTYLFXKOSA-N |
| Synonyms | Chlordione; 17α-Hydroxy-6-chloro-6-dehydroprogesterone; 17α-Hydroxy-6-chloropregna-4,6-diene-3,20-dione; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione |
Chlormadinone is a progestin which was never marketed.[1][2] An acylated derivative, chlormadinone acetate, is used clinically as a pharmaceutical drug.[1][2]
It was patented in 1958 and approved for medical use in 1963.[3] While chlormadinone is sometimes used as a synonym for chlormadinone acetate, what is almost always being referred to is chlormadinone acetate and not chlormadinone.
See also
References
- ^ Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 419. ISBN 978-0-412-46630-4. Retrieved 29 May 2012.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 215. ISBN 978-3-88763-075-1. Retrieved 29 May 2012.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 478. ISBN 9783527607495.