| Verifiedfields | changed |
|---|---|
| Watchedfields | changed |
| Verifiedrevid | 447926743 |
| Iupac name | (RS)-7-[2-[(1-hydroxy-1-phenylpropan-2-yl)amino]ethyl]-1,3-dimethylpurine-2,6-dione |
| Width | 250px |
| Tradename | Akrinor, Bifort, Praxinor |
| Cas number | 58166-83-9 |
| Atc prefix | C01 |
| Atc suffix | CA21 |
| Pubchem | 5489638 |
| Chembl | 2104207 |
| Chemspiderid | 4590188 |
| Unii | 0UYY5V4U2Q |
| Synonyms | Caphedrine; Cafedrin; Caphedrin; Kafedrin; Norephedrino-ethyltheophylline; 7-(2-(β-Hydroxy-α-methylphen-ethylamino)ethyl)theophylline |
| C | 18 |
| H | 23 |
| N | 5 |
| O | 3 |
| Smiles | C(CN[C@H]([C@H](O)C1=CC=CC=C1)C)N2C3=C(N(C)C(=O)N(C)C3=O)N=C2 |
| Stdinchi | 1S/C18H23N5O3/c1-12(15(24)13-7-5-4-6-8-13)19-9-10-23-11-20-16-14(23)17(25)22(3)18(26)21(16)2/h4-8,11-12,15,19,24H,9-10H2,1-3H3/t12-,15-/m0/s1 |
| Stdinchikey | UJSKUDDDPKGBJY-WFASDCNBSA-N |
Cafedrine (INN, BAN), sold under the brand name Akrinor among others, is a chemical linkage of norephedrine and theophylline and is a cardiac stimulant and antihypotensive agent used to increase blood pressure in people with hypotension.[1][2][3][4] It has been marketed in Europe, South Africa, and Indonesia.[4][5]
There has been concern about cafedrine as a potential performance-enhancing drug and doping agent in sports.[6]
See also
References
- ^ Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 205. ISBN 978-1-4757-2085-3. Retrieved 29 August 2024.
- ^ Pharmaceutical Manufacturing Encyclopedia. Volumes 1-4. Elsevier Science. 2013. p. 785. ISBN 978-0-8155-1856-3. Retrieved 29 August 2024.
- ^ Morton IK, Hall JM (1999). "Calcitonin gene-related peptide receptor antagonist". Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Dordrecht: Springer Netherlands. p. 59. ISBN 9789401144391.
- ^ Schweizerischer Apotheker-Verein (2000). Index Nominum 2000: International Drug Directory. Medpharm Scientific Publishers. p. 157. ISBN 978-3-88763-075-1. Retrieved 29 August 2024.
- ^ "Cafedrine". Drugs.com. Archived 6 January 2018 at the Wayback Machine. Retrieved 29 August 2024.
- ^ Wilson W, Derse E (2001). Doping in Elite Sport: The Politics of Drugs in the Olympic Movement. Human Kinetics. p. 15. ISBN 978-0-7360-0329-2. Retrieved 29 August 2024.