| Verifiedrevid | 411947982 |
|---|---|
| Width | 250px |
| Width 2 | 250px |
| Routes of administration | Oral[1] |
| Class | Psychoactive drug |
| Atc prefix | None |
| Duration of action | "Several hours"[1] |
| Cas number | 64778-75-2 |
| Pubchem | 15102780 |
| Chemspiderid | 10440102 |
| Unii | 4W9CQK6FS8 |
| Chembl | 159467 |
| Synonyms | B; 3,5-Dimethoxy-4-butoxyphenethylamine; 4-Butoxy-3,5-dimethoxyphenethylamine |
| Iupac name | 2-(3,5-dimethoxy-4-butoxyphenyl)ethan-1-amine |
| C | 14 |
| H | 23 |
| N | 1 |
| O | 3 |
| Smiles | COc1cc(cc(OC)c1OCCCC)CCN |
| Stdinchi | 1S/C14H23NO3/c1-4-5-8-18-14-12(16-2)9-11(6-7-15)10-13(14)17-3/h9-10H,4-8,15H2,1-3H3 |
| Stdinchikey | CHHALFOHMQNBAW-UHFFFAOYSA-N |
Buscaline (B), also known as 4-butoxy-3,5-dimethoxyphenethylamine, is a psychoactive drug of the phenethylamine and scaline families related to mescaline.[1][2][3] It is the derivative of mescaline in which the methoxy group at the 4 position has been replaced with a butoxy group.[1][2][3]
In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists buscaline's dose as greater than 150 mg orally and its duration as "several hours".[1][2][3] The effects of buscaline have been reported to include a slight change from baseline, no noticeable visual or auditory effects, uninteresting mental effects, body load, more bodily effects than mental effects, brief heart arrhythmia, stomach discomfort, light diarrhea, cold feet, and slight uncomfortableness.[1] No clear hallucinogenic effects were described.[1]
The chemical synthesis of buscaline has been described.[1] Analogues of buscaline include mescaline, escaline, proscaline, isoproscaline, isobuscaline, and thiobuscaline, among others.[1][2][3] Shulgin concluded based on investigation of buscaline that there would not be value in exploration of higher homologues of mescaline extended at the 4 position.[1]
Buscaline was first described in the scientific literature in 1930.[1] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]
See also
References
- ^ Buscaline Entry
- ^ Jacob P, Shulgin AT (1994). "Structure-Activity Relationships of the Classic Hallucinogens and Their Analogs". Hallucinogens: An Update. Vol. 146. National Institute on Drug Abuse Research Monograph Series. National Institute on Drug Abuse. pp. 74–91. PMID 8742795. Archived 13 July 2025 at the Wayback Machine.
- ^ Shulgin AT (2003). "Basic Pharmacology and Effects". Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived 13 July 2025 at the Wayback Machine.